Tumor Necrosis Factor‑Alpha, Highly Sensitive
Also known as: Cachectin, TNF Alpha HS, Cytokine, TNF Alpha HS
Use
This test measures levels of the cytokine Tumor Necrosis Factor‑Alpha (TNF‑α) using a highly sensitive immunoassay. It is predominantly used in contexts involving immune regulation and inflammatory processes; reportable interpretation may inform understanding of pathogenesis in inflammatory or immune-mediated disorders, though analytic performance characteristics are determined by Quest and results should not be used for definitive diagnosis without corroborating clinical evidence.
Special Instructions
Not provided.
Limitations
This test uses a kit not cleared or approved by the FDA; analytical performance characteristics have been internally validated by Quest and results should not be used alone for diagnosis without confirmation by other medically established methods.
Methodology
Immunoassay (Multiplex Protein Panel)
Biomarkers
TNF‑α
Protein
Result Turnaround Time
1-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL preferred; minimum 0.5 mL
Minimum Volume
0.5 mL
Container
Red‑top tube (no gel)
Collection Instructions
Collect blood in a red‑top tube (no gel); allow blood to clot ~10‑15 minutes at room temperature, centrifuge and separate serum.
Storage Instructions
Freeze as soon as possible.
Causes for Rejection
Gross hemolysis; gross lipemia; serum separator tube (SST); grossly icteric
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 9 months |
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