von Willebrand Antigen, Multimeric Analysis
Also known as: Multimeric Analysis, vWF Multimer, vWF, vW Factor Multimeric
Use
von Willebrand Antigen, Multimeric Analysis (also known as vWF Ag, Multimeric) assists in the categorization of von Willebrand disease subtypes, particularly useful when type 2 disease is suspected. It evaluates the multimeric structure of von Willebrand factor, aiding differentiation of qualitative versus quantitative deficiencies in hemostatic function.
Special Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3‑4 times. Centrifuge 15 minutes at 1500 g within one hour of collection, remove plasma avoiding the buffy layer, centrifuge again to obtain platelet‑poor plasma (PPP), freeze immediately, and transport on dry ice.
Limitations
Not provided.
Methodology
Other
Biomarkers
Result Turnaround Time
4-8 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
1 mL
Minimum Volume
0.2 mL
Container
light blue‑top tube containing 3.2% sodium citrate
Collection Instructions
Draw blood in a light blue‑top tube containing 3.2% sodium citrate, mix gently by inverting 3‑4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, avoiding the WBC/platelet buffy layer, place into plastic vial, centrifuge again, transfer platelet‑poor plasma to new plastic vial(s). Freeze immediately and send frozen.
Causes for Rejection
Hemolysis; received at room temperature; received refrigerated
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | Unacceptable |
| Frozen | 6 Months (or 30 days per some sites) |