2,3-Dinor 11 Beta-Prostaglandin F2 Alpha, 24 Hour, Urine
Use
Screening for mast cell activation disorders including systemic mastocytosis using 24‑hour urine specimens. Elevated 2,3‑dinor‑11beta‑prostaglandin F2 alpha (2,3 BPG) in urine is associated with systemic mastocytosis and sensitivity increases when combined with urinary leukotriene E4 and N‑methylhistamine. ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/Overview/606357?utm_source=openai))
Special Instructions
Not provided.
Limitations
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration. ([mayocliniclabs.com](https://www.mayocliniclabs.com/test-catalog/Overview/606357?utm_source=openai))
New York Approved
Methodology
Mass Spectrometry (LC‑MS/MS)
Biomarkers
2,3‑dinor 11beta‑prostaglandin F2 alpha
AnalyteCreatinine (normalized)
Analyte
LOINC Codes
- 94381-1 - 2,3-dinor 11B-PG F2a/Creat 24h Ur
- 2162-6 - Creat 24h Ur-mRate
- 20624-3 - Creat 24h Ur-mCnc
- 13362-9 - Specimen collect Time Ur
- 3167-4 - Specimen vol 24h Ur
- 94381-1 - 2,3-dinor 11B-PG F2a/Creat 24h Ur
Result Turnaround Time
3-8 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
5 mL
Minimum Volume
3 mL
Container
Plastic, 5‑mL tube (Sarstedt Aliquot Tube, T914)
Collection Instructions
24‑hour urine collection; refrigerate (preferred) or use acceptable preservatives (boric acid, sodium carbonate, 50% acetic acid) or ambient/frozen per guidelines; follow PDF urine preservative guidelines.
Patient Preparation
Discontinue aspirin for 2 weeks and NSAIDs for 72 hours prior to collection if medically feasible.
Storage Instructions
Refrigerated preferred; ambient acceptable (8 hours); frozen acceptable (30 days total).
Causes for Rejection
Specimens evaluated for suitability; insufficient total volume (<300 mL) may lead to cancellation and reflex to random urine version (23BPR).
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 8 hours |
| Refrigerated | 14 days |
| Frozen | 30 days |