Aldosterone, LC/MS

Casandra

Casandra Test Code LC45045Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 004374CPT Code 82088

Clinical Use

Order Test

Use

Evaluate patients with hypertension and possible hyperaldosteronism

Special Instructions

Instructions for suppression/stimulation tests involving serum aldosterone measurement are available in the online Endocrine Appendices, including Dexamethasone Suppression and ACTH Stimulation. Additionally, information about multiple-specimen testing can be found in the provided online documents.

Limitations

The test's performance characteristics were determined by Labcorp, and it has not been cleared or approved by the Food and Drug Administration. Factors such as decreased perfusion to the kidneys can lead to increased aldosterone and renin levels, affecting the test results. Renal conditions such as hemorrhage, dehydration, or narrowed renal arteries can also alter renin and aldosterone concentrations, potentially confounding the interpretation of results.

Test Details

Methodology

Mass Spectrometry

Biomarkers

Aldosterone

Analyte

Aldosterone • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

1763-2

Result Codes

1763-2

Result Turnaround Time

4-7 days

Specimen

Serum

Volume

1.2 mL

Minimum Volume

1 mL

Container

Red-top tube, gel-barrier tube, or lavender-top (EDTA) tube

Collection Instructions

If a tube other than gel-barrier is used, transfer separated serum or plasma to a plastic transport tube.

Patient Preparation

The patient should be taken off medications for at least three weeks prior to sample collection. Dietary sodium levels prior to testing can affect aldosterone levels. The patient should be ambulatory for at least 30 minutes before blood collection.