Allergen Profile, Cat, Dog and Horse, IgE With Component Reflex
Use
Allergen component testing offers advantages over the use of a complete extract, especially in poly-sensitized individuals, given its usefulness for distinguishing between sensitizations specific to singular species and sensitizations due to cross-reactivity.
Special Instructions
If Cat IgE is ≥0.35 kU/L, Fel d 1 IgE, Fel d 2 IgE, Fel d 4 and Fel d 7 IgE testing will be performed. For Dog IgE ≥0.35 kU/L, additional testing for Can f 1, Can f 2, Can f 3, Can f 4, Can f 5, and Can f 6 IgE will occur. If Horse IgE is ≥0.35 kU/L, Equ c 1 IgE will be tested.
Limitations
This test cannot identify all possible allergenic proteins and does not replace detailed clinical evaluation. The possibility of cross-reactivity among different mammalian species could lead to positivity in the absence of direct sensitization. The presence of specific IgE needs to be interpreted in conjunction with a patient’s clinical history due to potential for cross-reactivity causing misidentification.
Methodology
Immunoassay (Other)
Biomarkers
LOINC Codes
- 102115-3
- 6833-8
- 6098-8
- 6143-2
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.0 mL
Minimum Volume
2.0 mL
Container
Red-top tube or gel-barrier tube
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 18 months |
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