Allergen Profile With Component Reflexes, Respiratory–Area 19
Use
Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.
Special Instructions
Not provided.
Limitations
The results of the allergen-specific IgE test should be integrated with a patient's comprehensive clinical evaluation, as the use of component IgE testing generally enhances the evaluation over using whole extracts alone. Cross-reactivity between various allergens can pose interpretation challenges. Molecular similarity might cause sensitization to multiple components, complicating the diagnosis of primary sensitizers. Although the results can help diagnose allergies and guide therapeutic measures, they offer limited value in isolation without considering clinical symptoms.
Methodology
Immunoassay (CLIA)
Biomarkers
LOINC Codes
- 8251-1 - Service Cmnt-Imp
- 19113-0 - IgE SerPl-aCnc
- 6096-2 - D pteronyss IgE Qn
- 6095-4 - D farinae IgE Qn
- 10921-5 - B tropicalis IgE Qn
- 6833-8 - Cat Dander IgE Qn
- 6098-8 - Dog Dander IgE Qn
- 6041-8 - Bermuda grass IgE Qn
- 6228-1 - Red top grass IgE Qn
- 6152-3 - Johnson grass IgE Qn
- 6078-0 - Roach IgE Qn
- 6212-5 - P notatum IgE Qn
- 6075-6 - C herbarum IgE Qn
- 6025-1 - A fumgtus IgE Qn
- 6020-2 - A alternata IgE Qn
- 6029-3 - A pullulans IgE Qn
- 6189-5 - White Oak IgE Qn
- 6109-3 - White Elm IgE Qn
- 6113-5 - Gum-Tree IgE Qn
- 6282-8 - East White Pine IgE Qn
- 7604-2 - Cmn pigweed IgE Qn
- 6244-8 - Sheep Sorrel IgE Qn
- 6200-0 - Pellitory (offic) IgE Qn
- 6181-2 - Mouse Urine Prot IgE Qn
- 8251-1 - Service Cmnt-Imp
- 19113-0 - IgE SerPl-aCnc
- 6096-2 - D pteronyss IgE Qn
- 6095-4 - D farinae IgE Qn
- 10921-5 - B tropicalis IgE Qn
- 6833-8 - Cat Dander IgE Qn
- 6098-8 - Dog Dander IgE Qn
- 6041-8 - Bermuda grass IgE Qn
- 6228-1 - Red top grass IgE Qn
- 6152-3 - Johnson grass IgE Qn
- 6078-0 - Roach IgE Qn
- 6212-5 - P notatum IgE Qn
- 6075-6 - C herbarum IgE Qn
- 6025-1 - A fumgtus IgE Qn
- 6020-2 - A alternata IgE Qn
- 6029-3 - A pullulans IgE Qn
- 6189-5 - White Oak IgE Qn
- 6109-3 - White Elm IgE Qn
- 6113-5 - Gum-Tree IgE Qn
- 6282-8 - East White Pine IgE Qn
- 7604-2 - Cmn pigweed IgE Qn
- 6244-8 - Sheep Sorrel IgE Qn
- 6200-0 - Pellitory (offic) IgE Qn
- 6181-2 - Mouse Urine Prot IgE Qn
Result Turnaround Time
3-5 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.5 mL
Minimum Volume
Not provided
Container
Red-top tube or gel-barrier tube
Storage Instructions
Room temperature
Causes for Rejection
Inadequate labeling; gross hemolysis
