Allergen Profile With Component Reflexes, Respiratory–Area 5

Casandra

Casandra Test Code LC61927Version 1 (DRAFT)

Performing Lab

Lab LabcorpLab Test ID 607099CPT Codes 82785, 86003

Allergen Profile With Component Reflexes, Respiratory–Area 5

Clinical Use

Use

Detect possible allergic responses to various substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated (1) to determine whether an individual has elevated allergen-specific IgE antibodies; (2) if specific allergic sensitivity is needed to allow immunotherapy to be initiated; (3) when testing individuals for agents that may potentially cause anaphylaxis; (4) when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing); (5) if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms; (6) when an individual is unresponsive to medical management where identification of offending allergens may be beneficial.

Special Instructions

If Dog IgE levels are ≥0.35 kU/L, specific IgE for Can f 1, Can f 2, Can f 3, Can f 4, Can f 5, and Can f 6 will be performed. If Cat IgE levels are ≥0.35 kU/L, specific IgE for Fel d 1, Fel d 2, Fel d 4, and Fel d 7 will be performed.

Limitations

The results of this test should be interpreted considering patient clinical history. Allergen component testing may provide additional insights over whole extracts, especially in distinguishing between multiple allergens. Specific IgE levels are indicative of sensitization but must be correlated with clinical conditions to ascertain allergy presence or guide treatment.

Test Details