Allergic Bronchopulmonary Aspergillosis Panel II

Casandra

Casandra Test Code MC47553Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID FABP2CPT Codes 82785, 86001, 86003, 86331

Allergic Bronchopulmonary Aspergillosis Panel II

Clinical Use

Use

The Allergic Bronchopulmonary Aspergillosis Panel II aids in diagnosing allergic bronchopulmonary aspergillosis, a hypersensitivity reaction that can occur in some individuals with asthma or cystic fibrosis. The condition is characterized by an exaggerated immune response to Aspergillus fumigatus, a common fungus found in the environment. Identifying and managing this condition is critical in preventing further pulmonary deterioration and improving the quality of life in affected individuals. The panel measures levels of total IgE, specific IgE and IgG antibodies to Aspergillus fumigatus, and assesses the presence of immunodiffusion patterns, providing a comprehensive overview of the patient's immune response.

Special Instructions

Ensure that serum is handled properly post-collection: centrifuge and aliquot into a plastic vial, then refrigerate until it can be sent to the lab. The test is available Monday through Friday, and samples must be received on these days to begin analysis.

Limitations

The interpretation of results should be performed with caution, considering that elevated IgE levels can also be indicative of other allergic conditions or parasitic infections. Results from the Ouchterlony Gel Immunodiffusion test require careful interpretation as false positives can occur. Additionally, clinical correlation is necessary, and results should be considered alongside clinical findings and other diagnostic procedures. Variations in specimens or improper handling can also affect results, emphasizing the need for strict adherence to specimen collection and handling protocols.

Test Details