Antithrombospondin Type-1 Domain-Containing 7A (THSD7A) Antibody, IgG with Reflex to Titer
Also known as: THSD7A
Use
This test is recommended for the evaluation of membranous nephropathy in at-risk patients who test negative for PLA2R antibodies. A positive result for the THSD7A IgG antibody, in conjunction with other laboratory and clinical findings, supports a diagnosis of primary membranous glomerulonephritis. The presence of THSD7A antibodies can help identify cases of idiopathic membranous nephropathy that are not related to PLA2R antibody.
Special Instructions
If the THSD7A Antibody, IgG is positive, a reflex test to determine the antibody titer will be added, resulting in additional charges. The specimens must be processed quickly, separating serum from cells as soon as possible or within two hours of collection.
Limitations
This test was developed and its performance characteristics were determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration (FDA). It is performed in a CLIA-certified laboratory and is intended for clinical purposes. Results should be interpreted in conjunction with clinical findings and other diagnostic tests to confirm a diagnosis.
New York Approved
Methodology
Immunoassay (Indirect Fluorescent Antibody)
Biomarkers
LOINC Codes
- 93339-0
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.2 mL
Container
Transfer to an ARUP Standard Transport Tube
Collection Instructions
Separate serum from cells ASAP or within 2 hours of collection.
Storage Instructions
Refrigerated
Causes for Rejection
Hemolyzed, hyperlipemic, icteric, heat-treated or contaminated specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 month |
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