Aspergillus fumigatus, IgG Antibodies, Serum
Use
The test is useful for evaluating patients suspected of having hypersensitivity pneumonitis (HP) induced by exposure to Aspergillus fumigatus. It also aids in the evaluation of patients who have documented environmental exposures to high-humidity environments. The presence of IgG antibodies specific to Aspergillus fumigatus indicates sensitization to the fungus, but it should be used as supportive information for diagnosing HP, as a positive result alone does not confirm the diagnosis.
Special Instructions
Centrifuge and aliquot serum into a plastic vial. Use the Sarstedt Aliquot Tube, 5 mL (T914) for collection. The preferred collection container/tube is the Serum gel, and a red top is acceptable. The specimen volume required is 0.5 mL, with a minimum volume of 0.3 mL necessary for testing.
Limitations
Positive results for IgG antibodies to Aspergillus fumigatus may occur in individuals who are sensitized to this fungus but do not display symptoms consistent with hypersensitivity pneumonitis (HP). Negative results do not exclude the diagnosis of HP, as patients may be sensitized to different antigens. Positive results may also be found in patients with invasive aspergillosis and cavitary lung disease. The test is not FDA cleared or approved, and results should be interpreted in the context of clinical symptoms and imaging results.
New York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 26954-8
- 26954-8
Result Turnaround Time
2-4 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL
Minimum Volume
0.3 mL
Container
Serum gel or Red top
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross icterus is a cause for rejection.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 21 days |
| Frozen | 21 days |