Aspergillus Galactomannan Antigen by EIA, Bronchoscopy

Casandra

Casandra Test Code AR32488Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2003150CPT Code 87305

Aspergillus Galactomannan Antigen by EIA, Bronchoscopy

Also known as: ASPERAGB

Clinical Use

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Use

This test aids in the diagnosis of pulmonary aspergillosis by detecting Aspergillus galactomannan antigen in bronchoscopy specimens. The presence of this antigen indicates possible fungal infection caused by Aspergillus species, which can be critical for patients with weakened immune systems. The BAL (bronchoalveolar lavage) galactomannan index provides insight into whether the fungal infection might be present, although results should be interpreted alongside patient history, clinical signs and symptoms, and additional diagnostic tests such as cultures, histological examinations, and radiographic imaging.

Special Instructions

For serum specimens, refer to Aspergillus Galactomannan Antigen by EIA, Serum (ARUP test code 0060068). For sputum or tissue specimens, refer to Aspergillus Species by PCR (ARUP test code 3000265). Lower respiratory material must be collected via bronchoscopy and transferred to an ARUP Sterile Transport Tube. Specimens must be frozen during storage and transport.

Limitations

The test result is affected by factors such as specimen type and collection timing. It is important to interpret the results in the context of the patient's overall clinical picture because other diagnostic tests may be necessary to confirm a diagnosis. The test is specific for Aspergillus galactomannan and could potentially show false-positive or false-negative results, especially if used as the sole diagnostic method for aspergillosis. Tests done on other specimen types such as serum or sputum must employ different procedures or tests to obtain accurate results.

Test Details

FDA Approved