BOB.1
Use
BOB.1 (B-cell specific octamer binding protein-1) is a marker used to identify B-cells in germinal centers and mantle cells and lymphomas. This marker can be used to determine the lineage of CD20 negative B-cell neoplasms, and help differentiate classical Hodgkin's lymphoma (BOB1 negative) from primary mediastinal large B-cell lymphoma (positive).
Special Instructions
Not provided.
Limitations
Stated turn-around-times (TATs) are for clinical use only and subject to change based on biopharma protocol requirements. Final TATs will be specified in the biopharma study contract.
Methodology
Immunoassay (IHC)
Biomarkers
B-cell specific octamer binding protein-1
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin (NBF) for 6-72 hours (48-72 hours PREFERRED).
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus. All other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 Hours |