Casandra
Casandra Test Code QD74946Version 1 (DRAFT)
Performing Lab
BRAF Mutation Analysis
Also known as: BRAF Mutation Analysis, Oncomine Dx Target Test
Clinical Use
Order TestUse
Detects mutations in the BRAF gene, including clinically significant variants such as V600E (p.Val600Glu), which inform treatment options in metastatic cancers and melanomas.
Special Instructions
Not provided.
Limitations
This test is designed to detect gene mutations only. It is not intended to detect copy number changes or gene rearrangements.
Test Details
Methodology
Sanger
Biomarkers
BRAF
GeneSNV/Indel • Mutation • Categorical (e.g., Positive / Negative / Indeterminate)
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen Requirements
Specimen
Tumor Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Formalin-fixed, paraffin-embedded tissue block
Collection Instructions
For submission of paraffin block, tissue source and block ID are required on the requisition form. A pathology report must be submitted.
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | Unacceptable |
Related Tests
Other tests from different labs that may be relevant
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BRAF Codon 600 Mutation Detection by Pyrosequencing (Change effective as of 05/20/24: Refer to 3017203)
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BRAF V600E
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BRAF V600 Mutation Analysis
MPLN
