Cadmium, Random Urine

Casandra

Casandra Test Code AR48429Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 2011479CPT Code 82300

Cadmium, Random Urine

Also known as: U CAD RAND

Clinical Use

Order Test

Use

This test is useful in the assessment of chronic exposure to cadmium and determination of the cadmium body burden. In chronic exposures, the kidneys are the primary target organ, and urine cadmium concentrations can be indicative of cadmium toxicity. Symptoms vary based on exposure route and include tubular proteinuria, fever, headache, dyspnea, chest pain, conjunctivitis, rhinitis, sore throat, and cough. Ingestion of high concentrations of cadmium may cause vomiting, diarrhea, salivation, cramps, and abdominal pain.

Special Instructions

Patients should discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications before specimen collection upon physician advice. Abstinence from iodine-containing medications or contrast agents is recommended for at least one month prior to specimen collection for accurate elemental testing results.

Limitations

Elevated cadmium results may arise from skin or collection-related contamination, such as using non-trace element-free containers. If contamination is suspected, a second specimen collected in trace element-free containers should confirm results. High iodine concentrations may interfere with elemental tests.

Test Details

New York Approved

Methodology

Mass Spectrometry

Biomarkers

Cadmium

Analyte

Cadmium, Urine - per volume • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

Cadmium, Urine - ratio to CRT • Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Result Codes

35674-1
13828-9
5611-9

Result Turnaround Time

1-5 days

Specimen

Urine

Volume

8 mL

Minimum Volume

1 mL

Container

ARUP Trace Element-Free Transport Tubes (ARUP supply #43116)

Collection Instructions

Collect random urine. Avoid urine collection within 48 hours post gadolinium or iodine-containing contrast media use.

Patient Preparation

Encourage patients to stop taking nonessential nutrients, vitamins, and minerals per physician advice. Avoid iodine medications or contrast agents for at least one month before collection.