CD43 Immunostain, Technical Component Only
Use
This test is useful for the identification of T lymphocytes, monocytes, macrophages, granulocytes, plasma cells, and a subset of B lymphocytes. CD43 (cluster of differentiation 43) is expressed by T lymphocytes and myeloid cells including granulocytes and precursors, monocytes, macrophages, histiocytes, plasma cells, and megakaryocytes. In normal tonsil, CD43 will mainly show staining in T lymphocytes, histiocytes, and plasma cells.
Special Instructions
This test includes only the technical performance of the stain without pathologist interpretation. Technical-only stains should not be ordered with PATHC / Pathology Consultation, as they will be canceled if ordered together. Attach the green "Attention Pathology" address label (T498) and the pink Immunostain Technical Only label included in the kit to the transport container.
Limitations
The test does not include pathologist interpretation, which requires a separate Pathology Consultation order. Positive and negative controls are verified for appropriate immunoreactivity. Age of paraffin section, slide charge, and environmental factors can affect staining quality, and stability may vary based on the antigen. Best practices suggest cutting paraffin sections within 6 weeks and minimizing storage time and exposure to humidity and heat.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Storage Instructions
Minimize time slides are stored after being unpackaged. Limit exposure to high humidity and heat. Minimize exposure to plastics.
Causes for Rejection
Wet/frozen tissue, Cytology smears, Nonformalin fixed tissue, Nonparaffin embedded tissue, Noncharged slides, ProbeOn slides, Snowcoat slides
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |