CD61, technical only
Use
CD61 is an adhesion receptor found on various cells, including megakaryocytes, platelets, and monocytes. It plays a crucial role in platelet aggregation and acts as a receptor for fibrinogen and other factors. The expression of CD61 is typically low or absent in individuals with Glanzmann's thrombasthenia. It is also observed in most cases of megakaryocytic leukemias. This test is technical component only.
Special Instructions
Not provided.
Limitations
The test only includes the technical component and does not involve interpretation or consultation. Specimens not fixed according to specified guidelines may be rejected. Fixatives other than 10% NBF or B plus are unacceptable.
Methodology
Immunoassay (IHC)
Biomarkers
CD61
Protein
Result Turnaround Time
2 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (Fixed (Non-FFPE))
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours (48-72 hours preferred).
Storage Instructions
15°C to 25°C
Causes for Rejection
Specimens must be fixed in 10% NBF or B plus.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | ≤ 72 Hours |