Cedar, IgE, Serum
Use
The Cedar, IgE test is useful for establishing a diagnosis of an allergy to cedar and defining the allergen responsible for eliciting signs and symptoms. It identifies allergens responsible for allergic responses and/or anaphylactic episodes, confirms sensitization prior to beginning immunotherapy, and investigates the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens. Testing for IgE antibodies provides an indication of the immune response to allergens that may be associated with allergic disease.
Special Instructions
For this test, it is important to note that testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend upon the identification of allergen specificity. When ordering, if not done electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and test results must be interpreted in the clinical context. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding. Testing for IgE antibodies in patients previously treated with immunotherapy is not recommended to determine residual clinical sensitivity.
FDA ApprovedNew York Approved
Methodology
Immunoassay (Fluorescence Enzyme Immunoassay (FEIA))
Biomarkers
LOINC Codes
- 26049-7
- 26049-7
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen
Container
Plastic vial, Preferred: Serum gel, Acceptable: Red top
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK, Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |