Chaetomium globosum, IgE, Serum
Use
This test is useful for establishing the diagnosis of an allergy to Chaetomium globosum. It helps in defining the allergen responsible for eliciting signs and symptoms and identifying allergens responsible for allergic response and/or anaphylactic episodes. It can be used to confirm sensitization prior to beginning immunotherapy and to investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens.
Special Instructions
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend upon identification of allergen specificity. For a listing of allergens available for testing, see Allergens - Immunoglobulin E (IgE) Antibodies PDF. If not ordering electronically, complete, print, and send an Allergen Test Request (T236) with the specimen.
Limitations
Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and test results must be interpreted in the clinical context. False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases. The allergens chosen for testing often depend upon the age of the patient, history of allergen exposure, season of the year, and clinical manifestations.
New York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 7200-9
- 7200-9
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
0.3 mL for 1 allergen; more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space
Container
Preferred: Serum gel; Acceptable: Red top; Submission Container/Tube: Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis: OK; Gross lipemia: OK
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |