Chlamydia IgM and IgG Panel, Immunofluorescence, Serum

Casandra

Casandra Test Code MC15547Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID 619387CPT Codes 86631, 86632

Chlamydia IgM and IgG Panel, Immunofluorescence, Serum

Clinical Use

Use

This test aids in the clinical diagnosis of Chlamydia pneumoniae or Chlamydia psittaci infection, both of which are significant pathogens. Chlamydia pneumoniae is unique for being exclusively a human pathogen and accounts for a notable portion of pneumonia cases in humans. Chlamydia psittaci, on the other hand, is transmitted from infected birds and causes psittacosis, characterized by symptoms such as pneumonia, headache, and hepatosplenomegaly. The test uses immunofluorescence to detect IgM and IgG antibodies specific to these pathogens, thereby providing valuable diagnostic information in suspected cases of infection.

Special Instructions

If not ordering electronically, complete, print, and send an Infectious Disease Serology Test Request form with the specimen. For suspected Chlamydia trachomatis infection, separate nucleic acid amplification tests are recommended for accurate diagnosis due to limited sensitivity and specificity of serologic tests for Chlamydia.

Limitations

This test does not detect antibodies against Chlamydia trachomatis and is not suitable for diagnosing infections caused by this species. Antichlamydial IgG can persist for years, necessitating correlation with clinical history and other data. Early in a primary Chlamydia infection, antibodies might not be detectable; thus, a follow-up specimen may be needed. During primary infection, cross-reactive antibodies among Chlamydia species might occur. The test performance characteristics were determined in compliance with CLIA requirements, but it is not cleared or approved by the FDA.

Test Details

New York Approved