Use

This test is used to evaluate the electrolyte composition of urine and for studies on acid-base balance. It helps to distinguish whether a case of metabolic alkalosis is chloride-responsive (salt responsive) or not. By measuring urine chloride levels, it assists in differential diagnosis of metabolic alkalosis, especially in scenarios of chloride depletion, which can often be corrected through chloride repletion. It is also used to identify cases of chloride-resistant conditions such as those caused by endogenous or exogenous corticosteroids, which may require further investigation for potential ACTH or aldosterone producing neoplasms.