Coccidioides Antibody Reflex, Complement Fixation and Immunodiffusion, Serum
Use
Serologic testing for coccidioidomycosis. Detection of IgG antibody by complement fixation and precipitating IgM/IgG antibodies by immunodiffusion in serum, useful in patients with pulmonary or meningeal infection and history of travel or exposure to endemic areas. Over 90% of primary symptomatic cases detected by combined ID and CF testing.
Special Instructions
Only orderable as a reflex following the Coccidioides Antibody Screen with Reflex, Serum (COXIS).
Limitations
Antibodies (IgM and IgG) may persist after infection has resolved; CF titers may persist for months, making active infection interpretation complex.
New York Approved
Methodology
Immunoassay
Biomarkers
LOINC Codes
- 26625-4
- 33379-9
- 46182-2
- 46183-0
Result Turnaround Time
4-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
Not provided
Minimum Volume
1.2 mL
Storage Instructions
Refrigerated (preferred) 14 days; Frozen 14 days
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |