Corticosterone Quantitative by HPLC-MS/MS, Serum or Plasma
Also known as: CORTC
Use
The Corticosterone Quantitative by HPLC-MS/MS test is designed to measure the levels of corticosterone in serum or plasma. It is particularly useful in diagnosing and managing conditions related to the adrenal glands and overall endocrine function. This test helps in understanding the hormonal balance in various clinical situations, including stress and adrenal disorders, and can be a valuable tool in the differential diagnosis of endocrine conditions.
Special Instructions
A morning specimen is preferred for accurate results. The test is performed on specific days: Monday, Wednesday, and Friday, which may impact scheduling. Ensure proper specimen collection and handling to avoid any delays or issues with the analysis.
Limitations
This test is not cleared or approved by the FDA; thus, it is classified as a Laboratory Developed Test (LDT). The results are dependent on the proper handling and preparation of the specimen; grossly hemolyzed specimens are unacceptable and will lead to rejection. Given its nature as an LDT, the performance characteristics should be interpreted cautiously in non-compliant settings. It is designed for clinical purposes in a CLIA-certified laboratory but is not intended for use as a stand-alone diagnostic tool without consideration of clinical history and other diagnostic procedures.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2139-4
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
ARUP standard transport tube
Collection Instructions
Collect in a Serum separator tube. Also acceptable: Plain red, pink (K2EDTA), plasma separator tube, green (sodium heparin), or green (lithium heparin).
Patient Preparation
A morning specimen is preferred.
Storage Instructions
Refrigerated. Also acceptable: Frozen.
Causes for Rejection
Grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 1 week |
| Frozen | 6 months |
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