Cortisol (Dexamethasone Suppression Test) With Reflex to Dexamethasone
Also known as: Dexamethasone Suppression Test
Use
A reflex profile that tests adrenal suppression with dexamethasone.
Special Instructions
For detailed instructions on the administration and interpretation of the dexamethasone suppression test when evaluating patients for Cushing's syndrome, refer to the Dexamethasone Suppression Screening in the online Endocrine Appendix.
Limitations
The test may yield false-positive results in individuals who are obese, have had inadequate sleep, or are experiencing acute stress. These conditions can interfere with the proper assessment of adrenal function, leading to potential misdiagnosis.
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 2143-6
- 2143-6
- 14062-4
Result Turnaround Time
6-15 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1 mL
Container
Red-top tube, gel-barrier tube, lavender-top (EDTA) tube, or green-top (heparin) tube
Collection Instructions
Specimen must be separated from cells within one hour of venipuncture. Transfer serum or plasma to a plastic transport tube and freeze. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Storage Instructions
Freeze.
Causes for Rejection
Gross hemolysis
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 2 days |
| Refrigerated | 2 days |
| Frozen | 1 year |
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