Cortisol Urine Free by LC-MS/MS
Also known as: CORT UF
Use
The Cortisol Urine Free by LC-MS/MS test is intended to assist in the diagnosis and management of adrenal hyperfunction, particularly in ruling out Cushing syndrome. Cushing syndrome is characterized by excessive cortisol levels, and this test provides valuable quantitative analysis of cortisol in urine. Its high specificity due to the use of LC-MS/MS makes it suitable for catching deviations in cortisol excretion, which is crucial for accurate diagnosis.
Special Instructions
This test must be ordered by a healthcare provider. The specimen requires strict collection, handling, and transport conditions to maintain its validity. The collection must strictly adhere to either a 24-hour collection or a random urine sample, with the specific volume and time recorded for accurate testing.
Limitations
The test has limitations related to collection accuracy. Deviations in the collection time or urine volume can impact the results, and ratios of analytes to urine creatinine concentration may be necessary to assist result interpretation. Ambient temperature specimens and improperly stored specimens are unacceptable.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 35674-1
- 2162-6
- 34909-2
- 32009-3
- 19153-6
- 30211-7
- 2147-7
- 48767-8
Result Turnaround Time
1-5 days
Related Documents
For more information, please review the documents below
Specimen
Urine
Volume
4 mL
Minimum Volume
1 mL
Container
Transport tube with recorded total volume and collection time interval
Collection Instructions
Collect 24-hour or random urine. Refrigerate during collection.
Storage Instructions
Refrigerated transport is required.
Causes for Rejection
Room temperature specimens, acidified specimens, or specimens with preservatives are unacceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Unacceptable |
| Refrigerated | 2 weeks |
| Frozen | 6 months |
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