Cotton Fiber, IgE, Serum
Use
The test is useful for establishing a diagnosis of an allergy to cotton fiber. It helps define the allergen responsible for eliciting signs and symptoms. Moreover, it identifies allergens responsible for allergic response and/or anaphylactic episodes, helping to confirm sensitization prior to beginning immunotherapy. Testing for IgE antibodies is not beneficial in patients previously treated with immunotherapy or in those whose medical management doesn't depend on identifying allergen specificity.
Special Instructions
It is advised to complete, print, and send an Allergen Test Request (T236) with the specimen if not ordering electronically. For multiple allergens, consult the list of available allergens.
Limitations
The testing is not useful for patients previously treated with immunotherapy to determine the presence of residual clinical sensitivity or in cases where management does not depend on allergen specificity. There is the potential for false-positive results in patients with nonspecific IgE binding due to elevated serum IgE levels (>2500 kU/L). Therefore, results must be interpreted in the clinical context.
FDA ApprovedNew York Approved
Methodology
Immunoassay (FEIA)
Biomarkers
LOINC Codes
- 19737-6
- 19737-6
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.5 mL for every 5 allergens requested
Minimum Volume
(0.05 mL x number of allergens) + 0.25 mL deadspace
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Not specified, but gross hemolysis and lipemia are acceptable.
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 90 days |