CSF3R Mutation Analysis
Also known as: CSF3R
Use
The Colony Stimulating Factor 3 Receptor (CSF3R) gene is mutated in 59% of chronic neutrophilic leukemia (CNL) or atypical chronic myeloid leukemia (aCML). CSF3R mutation has been reported in 30-80% of leukemia arising in patients with severe congenital neutropenia. It has also been reported in 4% of colon cancer and 3% of small cell/squamous cell lung cancer. The presence of CSF3R mutation is important for diagnosis, classification, and prognosis of chronic myeloproliferative neoplasms.
Special Instructions
Not provided.
Limitations
Not provided.
Methodology
Sanger
Biomarkers
CSF3R
Gene
Result Turnaround Time
10 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
2 mL
Minimum Volume
Not provided
Container
EDTA tube
Storage Instructions
Use cold pack for transport, making sure cold pack is not in direct contact with specimen. For fresh samples: refrigerate before shipping and ship same day as drawn whenever possible. Do not freeze.