CXCL13 Immunostain, Technical Component Only
Use
CXCL13 (CXC motif chemokine ligand 13) is useful in the classification of nodal T-cell lymphomas with T-follicular helper (TFH) phenotype, and the diagnosis of follicular dendritic cell sarcoma. Immunohistochemical staining helps to assess the expression of CXCL13, offering insights into specific conditions related to T-cell lymphomas and aiding in the differential diagnosis based on cellular morphology and immunophenotypic profile.
Special Instructions
Not provided.
Limitations
The test does not include pathologist interpretation; only technical performance of the stain is offered. Interpretation requires Pathology Consultation for a comprehensive diagnostic evaluation. Age of a cut paraffin section can impact immunoreactivity, and stability thresholds are antigen-dependent. Best practice recommends paraffin sections be cut within 6 weeks to ensure optimal results. Nonformalin fixed tissue or nonparaffin embedded tissues will result in specimen rejection.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
CXCL13
Protein
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Preferred: 2 Unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections 4-microns thick. Acceptable: Formalin-fixed, paraffin-embedded tissue block.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |
| Refrigerated | Refrigerated |