Cytomegalovirus Antibody, IgM
Also known as: CMV IGM
Use
The Cytomegalovirus Antibody, IgM test is used to detect IgM antibodies specific to CMV in the serum, which may indicate a current or recent CMV infection. It is not recommended as a standalone test; IgM combined with IgG is preferred. This test is not suitable for diagnosing CMV infections in immunocompromised individuals. Molecular diagnostic tests like PCR are preferred in such cases. A detected result suggests a possible current or recent infection, but low levels of IgM may persist for over a year post-infection.
Special Instructions
Not provided.
Limitations
Serological testing is not suitable for evaluating active or reactivated CMV infection in immunocompromised patients. A negative IgM result does not exclude the possibility of a primary infection. Low levels of IgM antibodies may persist long after the initial infection, which can affect interpretation of results. Repeat testing in 10-14 days may be necessary if results are indeterminate.
FDA ApprovedNew York Approved
Methodology
Immunoassay (CLIA)
Biomarkers
Cytomegalovirus IgM
Protein
LOINC Codes
- 7853-5 - CMV IgM SerPl-aCnc
Result Turnaround Time
0-1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.5 mL
Container
ARUP Standard Transport Tube
Collection Instructions
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Label specimens as 'acute' or 'convalescent'.
Storage Instructions
Refrigerated storage is preferred.
Causes for Rejection
Contaminated, heat-inactivated, icteric, or grossly hemolyzed specimens.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 48 hours |
| Refrigerated | 2 weeks |
| Frozen | 1 year |
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