Cytomegalovirus Antibody, IgM

Casandra

Casandra Test Code AR25221Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0050553CPT Code 86645

Cytomegalovirus Antibody, IgM

Also known as: CMV IGM

Clinical Use

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Use

The Cytomegalovirus Antibody, IgM test is used to detect IgM antibodies specific to CMV in the serum, which may indicate a current or recent CMV infection. It is not recommended as a standalone test; IgM combined with IgG is preferred. This test is not suitable for diagnosing CMV infections in immunocompromised individuals. Molecular diagnostic tests like PCR are preferred in such cases. A detected result suggests a possible current or recent infection, but low levels of IgM may persist for over a year post-infection.

Special Instructions

This test should not be used for blood donor screening, associated reentry protocols, or for screening human cell, tissues, and cellular- and tissue-based products (HCT/P). Labels should clearly mark specimens as 'acute' or 'convalescent'.

Limitations

Serological testing is not suitable for evaluating active or reactivated CMV infection in immunocompromised patients. A negative IgM result does not exclude the possibility of a primary infection. Low levels of IgM antibodies may persist long after the initial infection, which can affect interpretation of results. Repeat testing in 10-14 days may be necessary if results are indeterminate.

Test Details

FDA Approved

New York Approved

Methodology

Immunoassay (CLIA)

Biomarkers

Cytomegalovirus IgM

Protein

Concentration / Level • Quantitative (Continuous) (e.g., copies/mL, % expression)

LOINC Codes

Order Codes

7853-5

Result Turnaround Time

0-1 days

Specimen

Serum

Volume

1 mL

Minimum Volume

0.5 mL

Container

ARUP Standard Transport Tube

Collection Instructions

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Label specimens as 'acute' or 'convalescent'.