Cytoplasmic Neutrophil Antibodies, Inflammatory Bowel Disease Panel, Serum
Use
Measurement of antineutrophil cytoplasmic antibodies as part of a profile to aid in distinguishing between ulcerative colitis and Crohn disease in patients for whom the specific diagnosis is unclear based on endoscopic, pathologic, and imaging evaluations. Not useful for determining the extent of disease or response to specific therapy.
Special Instructions
Not orderable as a standalone test; only as part of a larger profile such as the IBDP2 Inflammatory Bowel Disease Serology Panel, Serum.
Limitations
This test is unable to distinguish between ulcerative colitis and Crohn disease based solely on the presence of antineutrophil cytoplasmic antibodies or anti-Saccharomyces cerevisiae antibodies due to overlapping presence in these conditions. Results should be interpreted in conjunction with clinical findings, pathologic evaluations, and imaging studies. Some patients may not exhibit detectable antibody levels.
New York Approved
Methodology
Immunoassay (Indirect Immunofluorescent Assay (IFA))
Biomarkers
LOINC Codes
- 17355-9
- 17355-9
- 49308-0
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, gross lipemia, heat-treated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 21 days |
| Frozen | 21 days |