D240
Use
D2‑40 identifies a 40 kDa O‑linked sialoglycoprotein expressed by a variety of tissues, including fetal testes and testicular germ cell tumors. Anti‑D2 40 labels lymphatic endothelium but not vascular endothelium. In neoplastic tissue, immunostaining of lymphatic endothelium by anti‑D2 40 is useful for identifying lymphatic invasion of primary tumors, and is often positive in sarcomatoid malignant mesothelioma.
Special Instructions
Not provided.
Limitations
Not provided.
New York Approved
Methodology
Immunoassay (IHC)
Biomarkers
podoplanin
Protein
Result Turnaround Time
24 hours
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Formalin‑fixed, paraffin‑embedded (FFPE) tissue block is preferred; or one unbaked, unstained slide for H&E staining (required) plus two to three (2‑3) positively charged unstained slides, all cut at 4‑5 microns; block and slide identifiers must match requisition.
Storage Instructions
Use cold pack for transport, ensuring cold pack is not in direct contact with specimen. NYS clients: provide date and time of collection.