Deamidated Gliadin Antibodies, IgG
Also known as: DGP, IgG
Use
Detection of gliadin antibodies aids in the diagnosis and monitoring of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis.
Special Instructions
A negative IgA result in an untreated patient does not rule out gluten-sensitive enteropathies, especially when associated with IgG gliadin antibodies. It is important to consider selective IgA deficiency, a relatively frequent finding in celiac disease, which can affect the accuracy of antibody tests.
Limitations
False-positives are possible as other gastrointestinal disorders such as Crohn's disease, food protein intolerance, and post-infection malabsorption are known to induce circulating antigliadin antibody. Therefore, results should be interpreted in the context of clinical symptoms and other diagnostic tests.
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 58710-5
- 58710-5
Result Turnaround Time
2-3 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.3 mL
Container
Red-top tube or gel-barrier tube
Collection Instructions
Specimen should be free of bacterial contamination, hemolysis, and lipemia.
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
Other tests from different labs that may be relevant