Diphenhydramine Quantitative, Serum or Plasma
Also known as: DIPHENHYDR
Use
The diphenhydramine quantitative test measures the concentration of diphenhydramine in serum or plasma. It helps clinicians monitor and manage patients who have been exposed to diphenhydramine, commonly known as Benadryl, which is an antihistamine used for allergy relief. This test can be crucial for diagnosing diphenhydramine toxicity, managing overdose cases, and ensuring therapeutic levels in clinical treatment.
Special Instructions
This test is performed at NMS Labs and requires submission of separate specimens if multiple tests are ordered. It is not performed directly at ARUP Laboratories, and New York state approval has been granted for this test.
Limitations
The test is not cleared or approved by the US Food and Drug Administration. It is developed and its performance characteristics are determined by NMS Labs. Separator tubes are unacceptable as they can interfere with the test results. Stability limitations include ambient conditions for up to 1 month, refrigerated for up to 1 month, and frozen for up to 2 years.
New York Approved
Methodology
Mass Spectrometry
Biomarkers
LOINC Codes
- 3570-9
Result Turnaround Time
8-11 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
1 mL
Minimum Volume
0.4 mL
Container
ARUP standard transport tube
Collection Instructions
Separate from cells ASAP or within 2 hours of collection.
Patient Preparation
Plain red, lavender (K2EDTA), or pink (K2EDTA).
Causes for Rejection
Separator tubes.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 1 month |
| Refrigerated | 1 month |
| Frozen | 2 years |
Other tests from different labs that may be relevant