Ehrlichia chaffeensis Antibody, IgM by IFA

Casandra

Casandra Test Code AR46222Version 1 (DRAFT)

Performing Lab

Lab ARUP LaboratoriesLab Test ID 0051003CPT Code 86666

Ehrlichia chaffeensis Antibody, IgM by IFA

Clinical Use

Use

This test is most useful for detecting IgM antibodies during the acute phase of Ehrlichia chaffeensis infection. The presence of IgM antibodies suggests a current or recent infection. However, low levels of these antibodies may occasionally persist for more than 12 months after infection. It is recommended that this test be used in conjunction with other tests, such as IgG E. chaffeensis antibody tests and PCR testing, for a comprehensive evaluation. The causative agent of human monocytic ehrlichiosis (HME), E. chaffeensis, is detected by this test, and HME is a tick-borne disease most commonly reported as 'spotless' or rashless Rocky Mountain spotted fever in various regions of the United States.

Special Instructions

Parallel testing with IgG E. chaffeensis antibodies is recommended, and convalescent specimens should be received within 30 days of the acute specimen. Specimens must be marked clearly to distinguish between acute and convalescent samples. The test is performed twice a week on Tuesdays and Fridays.

Limitations

A single IgM result should be interpreted with caution as IgM antibodies can persist for more than a year post-infection, which may not necessarily indicate an active infection. It is critical to evaluate IgM results in the context of clinical symptoms and other laboratory findings to avoid misdiagnosis.

Test Details

New York Approved