Epithelia Panel #2, Serum

Casandra

Casandra Test Code MC52160Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID EPIP2CPT Code 86003

Epithelia Panel #2, Serum

Clinical Use

Use

The Epithelia Panel #2 is useful for establishing a diagnosis of allergies to guinea pig, hamster, mouse, rabbit, or rat. It identifies allergens responsible for allergic responses or anaphylactic episodes, confirms sensitization before starting immunotherapy, and explores the specificity of allergic reactions to insect venom, drugs, or chemicals. The test measures IgE antibodies in serum, indicating the immune response to allergens associated with allergic diseases.

Special Instructions

This test uses a pooled allergen reagent, reported with a single qualitative class result and concentration. It's not useful for patients previously treated with immunotherapy if determining residual clinical sensitivity is needed or where allergen specificity doesn't impact medical management. For a listing of allergens available for testing, refer to the Allergens - Immunoglobulin E (IgE) Antibodies document. Submission requires the use of a plastic vial and may require a completed Allergen Test Request form if not ordered electronically.

Limitations

This test provides a single result for the Epithelia Panel, but it cannot identify individual allergen responses within the panel. Further testing is required following a positive result to differentiate between individual allergens. False positives may occur in patients with markedly elevated serum IgE (>2500 kU/L). Despite measurable levels of IgE antibodies, some results may not indicate significant clinical sensitivity, necessitating cautious interpretation within the clinical context.

Test Details

FDA Approved