ERG Immunostain, Technical Component Only
Use
The test is used for the identification of erythroblast transformation specific (ETS)-related gene (ERG) protein expression. ERG is a member of the ETS family of transcription factors and is associated with the _TMPRSS2-ERG_ gene rearrangement observed in prostate cancers.
Special Instructions
Not provided.
Limitations
The test does not include pathologist interpretation, only the technical performance of the stain. Age of a cut paraffin section can affect immunoreactivity, and the stability of sections varies widely. Best practice is for paraffin sections to be cut within six weeks. Environmental factors can affect the charge of glass slides and alter slide staining, leading to inconsistent staining.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
ERG
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Collection Instructions
Formalin-fixed, paraffin-embedded tissue block or two unstained, positively charged glass slides (25- x 75- x 1-mm) per test ordered; sections 4-microns thick.
Causes for Rejection
Wet/frozen tissue, cytology smears, nonformalin fixed tissue, nonparaffin embedded tissue, noncharged slides, ProbeOn slides, Snowcoat slides