Euglobulin Clot Lysis Time
Use
The Euglobulin Clot Lysis Time test is used to evaluate fibrinolysis, particularly in assessing the function of the fibrinolytic system. It measures the time required for the lysis of a clotted sample. This test is typically performed when there is a suspicion of fibrinolysis-related disorders or when there is need to assess the potential of excessive bleeding due to fibrinolytic activity. The test provides insights into the breakdown of fibrin clots, a critical aspect of the body's ability to stop bleeding and form stable clots.
Special Instructions
Exercise should be prohibited prior to drawing the sample to prevent interference with test results. Additionally, avoid vigorous massaging of the vein, excessive fist pumping, or prolonged use of a tourniquet, as these actions can release plasminogen activator and affect the test results. It is important that the specimen is handled and sent in accordance with the specified guidelines to ensure the validity of the test results.
Limitations
This test is not suitable for patients with grossly hemolyzed, lipemic, or icteric samples as these conditions can lead to rejection. The test results are influenced by the stability and handling of the plasma sample; thus, prompt processing and freezing are crucial. The test's sensitivity and specificity in detecting fibrinolytic disorders depend on strict adherence to the collection and handling protocol. Cross-reactivity or interference from other coagulation factors or conditions may affect the test outcomes.
New York Approved
Methodology
Chromosomal / Cytogenetics
Biomarkers
LOINC Codes
- 3244-1
- 3244-1
Result Turnaround Time
5-18 days
Related Documents
For more information, please review the documents below
Specimen
Plasma
Volume
2 mL
Minimum Volume
1 mL
Container
Light-blue top (sodium citrate)
Collection Instructions
Collect blood in 3/2% sodium citrate light blue top tube. Centrifuge within 30 minutes after collection, freeze immediately. Send 2 mL platelet-poor plasma in plastic vial frozen.
Patient Preparation
Prohibit exercise prior to drawing sample. Avoid massage vein vigorously, pump fist excessively or leave tourniquet in place for prolonged period.
Causes for Rejection
Gross hemolysis, mild to gross lipemia, mild icterus
Stability Requirements
| Temperature | Period |
|---|---|
| Frozen | 21 days |