FISH, Prader‑Willi/Angelman Syndrome
Also known as: Prader/Willi, Angelman Syndrome
Use
This test is used to detect microdeletions of chromosome 15q11–q13 associated with Prader‑Willi syndrome using fluorescence in situ hybridization (FISH).
Special Instructions
Includes provider informed‑consent attestation required if ordering provider is located in states such as AK, AZ, DE, FL, GA, IA, MA, MN, MT, NV, NH, NJ, NY, OR, SC, SD, or VT, or if testing is performed in MA.
Limitations
Not FDA‑cleared or approved; validated under CLIA and used for clinical purposes only. (No other limitations explicitly provided.)
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
Result Turnaround Time
14 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL preferred, 1 mL minimum
Minimum Volume
1 mL
Container
sodium heparin (green‑top) tube; also acceptable: royal blue‑top or tan‑top sodium heparin
Collection Instructions
Clinical history and reason for referral required with test order.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Specimen viability decreases during transit; do not freeze; do not reject |
Other tests from different labs that may be relevant