Francisella tularensis Antibody, IgM, ELISA, Serum
Use
Evaluating the presence of IgM antibodies in patients with suspected tularemia caused by Francisella tularensis. Diagnostic testing options primarily include culture and serology. Serologic testing can support a diagnosis of current or recent tularemia in patients who are IgM positive. Human infection with F tularensis usually occurs through various routes such as inhalation, ingestion, or handling sick animals.
Special Instructions
This test should not be used as a test of cure as it is not quantitative. Patients may remain seropositive for months to years following resolution of disease. Only orderable as part of a profile. For more information see TULAB / Francisella tularensis Antibody, IgM and IgG, ELISA, Serum.
Limitations
False-negative results may occur if specimens are collected too early following symptom onset, prior to development of a detectable immune response. Repeat testing on new specimens collected 2 to 4 weeks later may be helpful. False-positive results might occur in patients with previous or current infections with Brucella species and potentially other cross-reactive pathogens. IgM antibodies may remain detectable for years in some individuals.
FDA ApprovedNew York Approved
Methodology
Immunoassay (ELISA)
Biomarkers
LOINC Codes
- 93716-9
- 93716-9
Result Turnaround Time
1 day
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
0.6 mL
Minimum Volume
Not provided
Container
Plastic vial
Collection Instructions
Centrifuge and aliquot serum into a plastic vial.
Causes for Rejection
Gross hemolysis, Gross lipemia, Gross icterus, Heat-inactivated specimen
Stability Requirements
| Temperature | Period |
|---|---|
| Refrigerated | 7 days |
| Frozen | 30 days |