Gastrin
Use
Gastrin is a polypeptide hormone crucial for digestive functions. It is naturally occurring in three forms: gastrin-14, gastrin-17, and gastrin-34. Its measurement aids in diagnosing disorders characterized by G-cell hyperplasia, including Zollinger-Ellison syndrome and G-cell hypersecretion. Understanding these levels can help address conditions related to hypergastrinemia and guide in clinical diagnosis of gastric disorders.
Special Instructions
Not provided.
Limitations
Specimens using any fixatives other than 10% neutral buffered formalin or B plus will be rejected. Final turnaround times may vary based on biopharma protocol requirements. Testing should be completed within 3 months after placing in ethanol for best results. Turnaround time is subject to change and will be determined by study contract.
Methodology
Immunoassay (IHC)
Biomarkers
Gastrin
Protein
Result Turnaround Time
8 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Collection Instructions
Fixative should be at a 20:1 fixative to tissue ratio, 10% neutral buffered formalin for 6-72 hours (48-72 hours PREFERRED). For long-term storage, transfer to 70% ethanol.
Storage Instructions
Store at 15°C to 25°C. Shipping should be ambient with a refrigerated gel pack to avoid extreme temperatures. Use of 70% alcohol is acceptable after initial fixation.
Causes for Rejection
Specimens fixed in any other fixatives will be rejected.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 Hours |
| Refrigerated | Indefinite |
| Frozen | Indefinite |