Glial Fibrillary Acidic Protein Immunostain, Technical Component Only
Use
Glial fibrillary acidic protein (GFAP) is an intermediate filament protein of 52 kDa found in glial cells, astrocytes, and ependymal cells. Immunoperoxidase staining for GFAP produces intense cytoplasmic staining of astrocytes, glial cells, and ependymal cells in normal brain. In neoplastic tissues, GFAP is useful for the identification of glial tumors such as astrocytomas and ependymomas.
Special Instructions
Not provided.
Limitations
This test does not include pathologist interpretation, only technical performance of the stain. If interpretation is required, order PATHC / Pathology Consultation for a full diagnostic evaluation or second opinion of the case. Age of a cut paraffin section can affect immunoreactivity. Stability thresholds vary widely among published literature and are antigen dependent. The charge of glass slides can be affected by environmental factors and subsequently may alter slide staining.
FDA ApprovedNew York Approved
Methodology
Immunoassay (IHC)
Biomarkers
GFAP
Protein
LOINC Codes
- Order only;no result
Result Turnaround Time
1-3 days
Related Documents
For more information, please review the documents below
Specimen
Tissue (FFPE)
Volume
Not provided
Minimum Volume
Not provided
Container
Immunostain Technical Only Envelope
Causes for Rejection
Wet/frozen tissue Cytology smears Nonformalin fixed tissue Nonparaffin embedded tissue Noncharged slides ProbeOn slides Snowcoat slides