Golimumab and Anti-Golimumab Antibody, DoseASSURE™ GOL
Also known as: DoseASSURE, Golimumab, Simponi
Use
The Golimumab and Anti-Golimumab Antibody, DoseASSURE™ GOL test is used for therapeutic drug monitoring of golimumab levels in serum. It assesses the presence and concentration of golimumab, a biologic used in the treatment of certain autoimmune conditions like rheumatoid arthritis and ulcerative colitis. The presence of anti-golimumab antibodies can suggest immunogenicity which may impact drug efficacy.
Special Instructions
Not provided.
Limitations
Failure of golimumab therapy may not always be due to the presence of anti-golimumab antibodies, and the absence of these antibodies does not guarantee treatment effectiveness. High serum biotin concentrations can interfere with assay results.
Methodology
Immunoassay (ECLIA)
Biomarkers
Anti-Golimumab Antibody
AnalyteGolimumab
Analyte
LOINC Codes
- 87406-5 - Golimumab SerPl IA-mCnc
- 87406-5 - Golimumab SerPl IA-mCnc
- 87407-3 - Golimumab Ab SerPl IA-mCnc
Result Turnaround Time
5-12 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3.0 mL
Minimum Volume
1.0 mL
Container
Serum-gel tube, red-top tube, or lavender-top (EDTA) tube
Collection Instructions
Serum/plasma must be separated from cells within 45 minutes of venipuncture. Send serum/plasma in a plastic transport tube.
Patient Preparation
Stop biotin 72 hours prior to sample collection.
Storage Instructions
Freeze.
Causes for Rejection
Gross hemolysis, gross lipemia
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 7 days |
| Refrigerated | 7 days |
| Frozen | 7 days Stable x3 freeze/thaw cycles |
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