Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Chlamydia/Gonococcus/Trichomonas, NAA With Reflex to Human Papillomavirus (HPV) (Aptima) When ASC-U, ASC-H, LSIL, HSIL, AGUS With Reflex to HPV Genotypes 16 and 18,45
Use
Diagnose primary or metastatic neoplasm. This test aids in the diagnosis of sexually transmitted HPV infection and in the triage of patients with an abnormal Pap test result. Detect Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis. High-risk HPV test is used for types 16,18,31,33,35,39,45,51,52,56,58,59,66, and 68, without differentiation of the individual type. Positive high risk HPV test results reflex the sample for genotyping of types 16 and 18/45.
Special Instructions
Not provided.
Limitations
The test may fail to provide adequate evaluation if the ectocervical, endocervical, or vaginal cell population is insufficient. Excessive lubricant use can interfere with examination, making results unsatisfactory. Multiple tests from the same specimen may also limit the available volume for accurate testing. A negative result does not rule out HPV infection due to possible low-level infection or sampling errors.
Methodology
PCR-based (NAA)
Biomarkers
LOINC Codes
- 47527-7 - Cytology Cvx/Vag Doc Thin Prep
- 47528-5 - Cytology Cvx/Vag Doc Cyto
- 19764-0 - Stat of Adq Cvx/Vag Cyto-Imp
- 19773-1 - Recom F/U Cvx/Vag Cyto
- 19763-2 - Specimen source Cvx/Vag Cyto
- 52797-8 - Dx ICD code
- 22636-5 - Path report.relevant Hx Spec
- 22638-1 - Path report.comments Imp Spec
- 22639-9 - Path report.supplemental reports Spec
- 19767-3 - Cytologist Cvx/Vag Cyto
- 19769-9 - Pathologist Cvx/Vag Cyto
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Cervical Swab
Volume
ThinPrep® vial
Minimum Volume
Not provided
Container
ThinPrep® vial
Collection Instructions
ThinPrep® Vial − Broom or Brush/Spatula: Use broom-like or brush/spatula collection techniques to obtain cervical specimens, following specific instructions to ensure proper sampling.
Patient Preparation
Avoid douches 48 to 72 hours prior. Do not collect during or shortly after menses.
Storage Instructions
Maintain at room temperature. Process within 21 days of collection.
Causes for Rejection
Improper collection, inadequate specimens, improper labeling, leaks, insufficient quantity, expired vial, frozen specimens, and male specimens. Expired specimens beyond 21 days for Pap and HPV, or 7 days for Chlamydia, Gonococcus, and Trichomonas.