Gynecologic Pap Test (Image-guided), Liquid-based Preparation and High-risk HPV (Cobas®) With HPV Genotypes 16 and 18
Use
Diagnose primary or metastatic neoplasm. The HPV test specifically identifies types HPV16 and HPV18 while concurrently detecting the rest of the high-risk types: 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68 without further specific differentiation.
Special Instructions
Not provided.
Limitations
Suboptimal results may occur if there is failure to obtain adequate ectocervical, endocervical, or vaginal cell populations. The use of lubricating jelly on the vaginal speculum may interfere with cytologic examination leading to unsatisfactory results. Moreover, the availability of specimen volume for HPV testing might be limited if used for multiple tests. The detection of high-risk HPV depends on the number of copies present and may be influenced by collection methods, patient factors, and infection stage.
Methodology
Other
Biomarkers
LOINC Codes
- 47528-5
- 19764-0
- 19773-1
- 19763-2
- 52797-8
- 22636-5
- 22638-1
- 22639-9
- 11546-9
- 71431-1
- 77399-4
- 77400-0
- 11502-2
- 8251-1
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Cervical Swab
Volume
ThinPrep® vial
Minimum Volume
Not provided
Container
ThinPrep® vial
Collection Instructions
Use brush/spatula technique to collect from ectocervix and endocervical canal. Insert the brush into the canal and rotate 1/4 to 1/2 turn. Rotate in PreservCyt® solution 10 times before discarding brush. Use plastic spatula for ectocervix and swirl in ThinPrep® 10 times before discarding spatula. Secure by tightening the cap past the torque line.
Patient Preparation
Avoid douches 48 to 72 hours before exam. Do not collect during or shortly after menstruation. Avoid excessive use of lubricating jelly.
Storage Instructions
Maintain at room temperature. Pap processing within 21 days; may be stored for six months before COBAS® HPV test.
Causes for Rejection
Improper collection, inadequate or improperly labeled specimens, frozen specimens, specimens leaked in transit, insufficient quantity, name discrepancies, specimens from males, specimens older than 21 days for Pap or six months for HPV, excessively bloody specimens.