Gynecologic Pap Test (Image-guided), Liquid-based Preparation and Human Papillomavirus (HPV) (Aptima®) With Reflex to HPV Genotypes 16 and 18,45
Use
Diagnose primary or metastatic neoplasm. High-risk HPV test is used for types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68, without differentiation of the individual type. If the Pap evaluation is within normal limits and the initial HPV test is positive, then the residual specimen will be tested individually for high-risk HPV types 16 and 18,45.
Special Instructions
Not provided.
Limitations
An inadequate sample from the ectocervical, endocervical, or vaginal cell population can hinder evaluation. The use of excessive lubricant can interfere with examination results. The test only detects 14 common high-risk HPV types and a negative result doesn't rule out infection due to potential low levels of the virus or sample inadequacies. The same specimen's use for multiple tests might limit its availability for retesting.
Methodology
PCR-based (Nucleic acid amplification (NAA))
Biomarkers
High-risk HPV
Microorganism
LOINC Codes
- 47527-7
- 47528-5
- 19764-0
- 19763-2
- 52797-8
- 19767-3
- 19769-9
- 11546-9
- 59420-0
- 8251-1
Result Turnaround Time
3-6 days
Related Documents
For more information, please review the documents below
Specimen
Other
Volume
ThinPrep® vial
Minimum Volume
Not provided
Container
ThinPrep® vial
Collection Instructions
Using the broom-like technique, sample the cervix by inserting the brush and rotating it five times. Rinse the brush in the PreservCyt® solution by pushing it into the vial bottom 10 times, followed by twirling. For the brush/spatula method, rotate the brush in the endocervical canal followed by swirling in the solution.
Patient Preparation
Avoid douches 48 to 72 hours before the examination. Do not collect during or immediately after menstruation.
Storage Instructions
Maintain at room temperature. Pap processing must be done within 21 days of collection.
Causes for Rejection
Incorrect collection; inadequate specimen; incorrect labeling; specimen leakage; insufficient quantity; name discrepancies; specimen more than 21 days old or submitted on male; expired specimen vial; frozen or SurePath™ vial specimen.