Hematologic Disorders, Chromosome Hold, Varies
Use
This test is used for holding bone marrow or peripheral blood specimens in the laboratory, delaying chromosome analysis while a preliminary morphologic assessment is conducted. Conventional chromosome analysis is the gold standard for identifying common chromosome abnormalities in hematologic malignancies. Depending on the diagnosis, fluorescence in situ hybridization assays may also be used if they provide more informative insights about chromosome anomalies with prognostic significance, especially for plasma cell proliferative disorders.
Special Instructions
Not provided.
Limitations
This test does not cover fluorescence in situ hybridization (FISH) assays and may not be recommended for plasma cell neoplasms. The chromosome analysis is postponed until the preliminary morphologic assessment is complete, which can delay specific diagnosis. Chromosome analysis will not be performed if the specimen shows no evidence of malignancy, and additional testing like FISH might provide more relevant information depending on the case.
New York Approved
Methodology
Chromosomal / Cytogenetics
Biomarkers
LOINC Codes
- 50397-9 - Mol dx interp Bld/T Ql
- 69965-2 - Clinical cytogeneticist review
- 42349-1
- 31208-2 - Specimen source
- 48767-8 - Annotation comment Imp
- 85069-3 - Lab test method
- 18771-6 - Provider signing name
Result Turnaround Time
7-10 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
1 to 2 mL
Minimum Volume
1 mL
Container
Yellow top (ACD)
Collection Instructions
Invert several times to mix bone marrow.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |
| Refrigerated | Refrigerated |