Hematologic Specified FISH, Varies
Use
This test is useful for the detection of specific chromosomal abnormalities in hematologic malignancies. By using gene-specific probes and various FISH probe strategies, it helps characterize chromosome abnormalities for diagnostic, prognostic, and therapeutic purposes. FISH offers a reliable method of identifying genetic alterations that can inform treatment decisions and patient management in hematologic disorders.
Special Instructions
Not provided.
Limitations
This test is not approved by the US Food and Drug Administration and is intended for use as an adjunct to existing clinical and pathologic information. While bone marrow is the preferred specimen type, a blood specimen may be used if malignant cells are present in the blood. The absence of an abnormal clone does not rule out the presence of a neoplastic disorder.
New York Approved
Methodology
Chromosomal / Cytogenetics (FISH)
Biomarkers
LOINC Codes
- In Process
- 50397-9 - Mol dx interp Bld/T Ql
- 69965-2 - Clinical cytogeneticist review
- 93356-4 - Cells w cytogenetic abnl Bld/T
- 62356-1 - Chrom analy result (ISCN)
- 42349-1
- 78040-3 - FISH probe target gene Lab Device
- 31208-2 - Specimen source
- 85069-3 - Lab test method
- 48767-8 - Annotation comment Imp
- 62364-5 - Test performance info Spec
- 18771-6 - Provider signing name
Result Turnaround Time
9-12 days
Related Documents
For more information, please review the documents below
Specimen
Bone Marrow
Volume
2-3 mL
Minimum Volume
1 mL
Container
Yellow top (ACD); Green top (Heparin) or Lavender top (EDTA) acceptable
Collection Instructions
Preferably send the first aspirate from the bone marrow collection. Invert several times and send in the original tube. Do not aliquot.
Causes for Rejection
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | Ambient (preferred) |
| Refrigerated | Refrigerated |