Hepatitis C Virus (HCV) by Quantitative NAAT with Reflex to HCV Genotype by Sequencing
Also known as: HCVQT GR
Use
This test is used to confirm active HCV infection following a positive HCV screen. It detects HCV RNA to confirm the virus is replicating, indicating active infection. The test reflexes to genotype to aid in prognosis and treatment selection. It can be used as an aid in the management of patients with HCV undergoing antiviral therapy, allowing for the measurement of HCV RNA levels at various stages of treatment to determine response.
Special Instructions
Not provided.
Limitations
A result of "Not Detected" does not rule out the presence of inhibitors in the patient specimen or hepatitis C virus RNA concentrations below the detection level of the test. The test cannot differentiate between subtype 1a and 1b of the virus and, in rare cases, may misclassify type 6 as type 1. This test is not suitable for blood donor screening, associated reentry protocols, or for screening human cells, tissues, and cellular tissue-based products (HCT/P).
New York Approved
Methodology
PCR-based (RT-PCR)
Biomarkers
Hepatitis C Virus
MicroorganismHepatitis C Virus Genotype
Microorganism
LOINC Codes
- 11011-4 - HCV RNA SerPl NAA+probe-aCnc
- 38180-6 - HCV RNA SerPl NAA+probe-Log IU
- 11259-9 - HCV RNA SerPl Ql NAA+probe
Result Turnaround Time
1-8 days
Related Documents
For more information, please review the documents below
Specimen
Serum
Volume
3 mL
Minimum Volume
1.8 mL
Container
ARUP standard transport tube (ARUP supply #15824)
Collection Instructions
Separate from cells within 24 hours of collection.
Causes for Rejection
Heparinized specimens
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 24 hours |
| Refrigerated | 72 hours |
| Frozen | 3 months |
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