HIV-1 and HIV-2 Antigen and Antibody Diagnostic Evaluation, Serum

Casandra

Casandra Test Code MC42347Version 1 (DRAFT)

Performing Lab

Lab Mayo Clinic LabLab Test ID HIVDSCPT Codes 86701, 86702, 87389, 87535, 87538

HIV-1 and HIV-2 Antigen and Antibody Diagnostic Evaluation, Serum

Clinical Use

Use

This test is useful for detecting HIV-1 and HIV-2 infection in symptomatic patients older than 2 years. It is also used for follow-up testing of symptomatic individuals with reactive rapid HIV test results. It should not be used as a screening or confirmatory test for blood donor specimens.

Special Instructions

If the specimen is obtained from autopsy or cadaver blood sources, order HV1CD / HIV-1 and HIV-2 Antibodies for Cadaveric or Hemolyzed Specimens, Serum. This test should not be used to screen or test asymptomatic, nonpregnant individuals. This test should not be requested for maternal/newborn HIV screening for specimens originating in New York State.

Limitations

The electrochemiluminescence immunoassay used in this test does not differentiate among reactivity with HIV-1 p24 antigen, HIV-1 antibody, and HIV-2 antibody. A reactive screening test result is not diagnostic for HIV infection and should be considered preliminary. False-positive or false-negative results may occur, particularly in individuals with experimental HIV-1 vaccines, individuals undergoing antiretroviral therapy, or those taking pre-exposure or post-exposure prophylaxis. Assay performance characteristics have not been established for grossly hemolyzed, lipemic, icteric, heat-inactivated specimens, or specimen types other than serum.

Test Details

FDA Approved