HLA-A Genotype
Also known as: HLA A
Use
The HLA-A Genotype test is intended to be useful in immunization and vaccination trials or to aid in the clinical diagnosis of diseases strongly associated with the HLA-A locus. This HLA typing can help in determining compatibility and identifying potential disease associations with specific HLA alleles.
Special Instructions
This test is performed by a non-ARUP laboratory, specifically at the Histocompatibility & Immunogenetics Laboratory, University of Utah Health. It is important to specify antigen details when ordering this test.
Limitations
The test does not establish a diagnosis solely based on the presence of a disease-associated HLA combination. If fewer than two alleles are reported for a locus, homozygosity might be present. Diagnostic errors could occur due to primer or probe site mutations. This test is not adequate for comprehensive HLA evaluation necessary for clinical hematopoietic stem cell transplantation; pre-transplant allele matching should consider more comprehensive panels that include multiple HLA types.
New York Approved
Methodology
PCR-based (PCR)
Biomarkers
LOINC Codes
- 38548-4
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
5 mL
Minimum Volume
3 mL
Container
Lavender (EDTA), Pink (K2EDTA), or Yellow (ACD Solution A or B) tube
Storage Instructions
Refrigerated
Causes for Rejection
Specimens collected in green (sodium or lithium heparin) tubes
Stability Requirements
| Temperature | Period |
|---|---|
| Room Temperature | 72 hours |
| Refrigerated | 1 week |
| Frozen | Unacceptable |
Other tests from different labs that may be relevant