HLA B*57:01, Abacavir Hypersensitivity HLA Association Test
Also known as: Abacavir Hypersensitivity HLA Association, B*5701, B*57:01, B5701, HLA Antigen B*57:01
Use
Determine the presence of B57 antigen
Special Instructions
Not provided.
Limitations
Even with appropriate precautions, an occasional specimen may not be satisfactory for testing. In such cases, an additional specimen should be collected for testing. Moreover, a negative result for HLA-B*57:01 does not preclude the possibility of developing an allergic response to abacavir. The genotype result should not substitute for clinical vigilance and patient management in abacavir-containing regimens.
Methodology
PCR-based (SSOP)
Biomarkers
No genes
Gene
LOINC Codes
- 42358-2 - HLA-B*57:01 Spec Ql
- 42358-2 - HLA-B*57:01 Spec Ql
Result Turnaround Time
3-7 days
Related Documents
For more information, please review the documents below
Specimen
Whole Blood
Volume
7 mL
Minimum Volume
3 mL
Container
Lavender-top (EDTA) tube
Storage Instructions
Maintain blood specimen at room temperature.
Causes for Rejection
Hemolysis; clotted specimen; insufficient amount of DNA on buccal swabs
Other tests from different labs that may be relevant